Law Offices of Arnold Laub
A PROFESSIONAL CORPORATION

CORPORATE HEADQUARTERS * THE LAUB BUILDING
807 Montgomery Street * San Francisco, CA 94133

PRESS RELEASE

25-YEAR OLD WOMAN DIES AS A RESULT OF A BRAIN ANEURYSM SUFFERED WHILE TAKING DIET DRUGS, FEN-PHEN.

THE LAW OFFICES OF ARNOLD LAUB and the law offices of LIEFF, CABRASER, HEIMANN & BERNSTEIN, LLP announce an investigation into the new study of brain damage caused by taking diet drugs. The law firms previously filed a class action in San Francisco federal district court which named as defendants the manufacturers of the prescription diet drugs known as Fenfluramine (a.k.a. Pondimin), Phentermine (a.k.a. Fen-Phen), and Dexfenfluramine (a.k.a. Redux). ARNOLD LAUB stated, "Our client, MELANIE FRANKS, died from a brain aneurysm suffered while she was taking the prescription diet drugs, Fenfluramine and Phentermine (aka, Fen-Phen). A recent study from the National Institute of Mental Health establishes that brain damage can occur as a result of taking a fenfluramine drug. I am concerned that other individuals may not be aware of the risk of brain damage inherent in taking the diet drugs".

As reported in the Journal of the American Medical Association last week, the popular diet drugs, Redux and Pondimin are believed to have caused brain damage in laboratory animals at doses roughly equivalent to those taken by humans. The study's lead researcher, Dr. Una McCann (NIMH) said, "The serotonin is gone in certain brain areas where you would expect to find it...If the same thing occurs in people, it could lead to behavior problems". She concluded that relatively small amounts of the drugs "amputate the neurons" that store the neurotransmitter Serotonin.

Fenfluramines affect serotonin levels in the brain, which play an important role in mood, sleep patterns, regulation of anxiety and thought processes. Some 50 million people worldwide take the drugs, which suppress appetite evidently by altering the way the brain cells release the neurotransmitter Serotonin.

This newest revelation, combined with the Mayo Clinic report (7/8/97), which cites an unusual valvular heart disease in patients who had taken a combination of Fen-Phen, as well as the documented sometimes fatal disease of the heart and lungs, Primary Pulmonary Hypertension (PPH), is sufficient evidence to alert the manufacturers to pull the drugs from the market before more people suffer heart, lung and brain damage, or even death. Although both of the drugs have been approved by the FDA individually, their combination use has not been approved.

Bill Boni, spokesman for Interneuron Pharmaceuticals, the developer of Redux, says this year's projected sales of $200 million are on target. Doctors wrote an estimated 18 million monthly prescriptions for these drugs in the United States last year alone.

The lawsuit requests as part of its prayer that there be a medical monitoring fund established to enable those people who have taken these diet supplement prescription drugs to monitor the existence of dangerous side effects that may have been caused by the drugs.

We will hold a press conference at THE LAW OFFICES OF ARNOLD LAUB, The Laub Building, 807 Montgomery St., San Francisco on Thursday, September 4th, 10:00 a.m. The mother of our deceased client, LANA CAPERTON, will be available on a conference call from Texas to discuss this case in more detail and answer any related questions. We hope you, or a member of your staff, can attend.

Contact: ARNOLD LAUB (415) 362-0101, ext. 200
ROGER L. SISNEROS, ext. 295
ISABELLE V. RUSSELL, ext. 227

TEL:415/362-0101 * FAX:415/296-8841 * INTERNET: alaub@laub.com

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